Vikings Game Sunday: Vikings vs. 49ers odds and prediction for Week 12 NFL game

(Photo by Kirby Lee-USA TODAY Sports) Dalvin Cook
(Photo by Kirby Lee-USA TODAY Sports) Dalvin Cook /

After a big win over the Green Bay Packers last week, can the Minnesota Vikings get another impressive victory against the San Francisco 49ers in Week 12?

Following their upset win over the Green Bay Packers in Week 11, the Minnesota Vikings will attempt to earn their third victory in a row when they travel to face the San Francisco 49ers on Sunday.

The Vikings and 49ers are both sitting with 5-5 records, so this weekend’s matchup between the two teams could have a gigantic impact on the NFC playoff picture at the end of the year. Will Minnesota be able to increase their win streak to three and get their record above .500 for the first time since the 2019 season?

Minnesota Vikings vs. San Francisco 49ers odds Week 12

Point Spread:

  • Vikings +3.0 (+100)
  • 49ers -3.0 (-120)


  • Vikings +150
  • 49ers -170


  • 49.0 points
    • Over  -110
    • Under -110

(Odds via WynnBet)

Minnesota Vikings vs. San Francisco 49ers prediction Week 12

With Minnesota coming off a big emotional win, Sunday’s matchup with the 49ers seems like it’s set up perfectly for the Vikings to come back down to earth with a loss.

However, this has been a different Minnesota team during the last two weeks. They have been a team that has relied on their offensive playmakers like Justin Jefferson, Kirk Cousins, and Dalvin Cook more than their defense, which is a completely different feeling for head coach Mike Zimmer.

This new-and-improved aggressive Vikings offense was able to have success against a talented defense last week and they should be able to do it again on Sunday against the 49ers.

Prediction: Vikings win

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