San Francisco will run for over 150 yards
A big reason why the Vikings need to get off to a fast start is because of the 49ers’ run-oriented attack. San Francisco ranks eighth in the NFL with 123.2 rushing yards per game but has averaged 170.5 yards on the ground over their past two games.
While Elijah Mitchell is unlikely to play due to a finger injury, the combination of Jeffrey Wilson and Trey Sermon have made for an effective committee. San Francisco has even thrown Deebo Samuel into the backfield, which adds another wrinkle for the Vikings to stop.
The Vikings’ run defense continues to struggle, allowing 127 rushing yards per game and an NFL-high 4.8 yards per carry this season. While those numbers are rough, they could get even worse with all four starting defensive linemen out for Sunday’s game.
If the Vikings don’t get out to a lead, the 49ers will be able to run the ball and control the clock. That could put pressure on the Minnesota offense and lead to a disappointing result.