Chiefs vs. Vikings prediction, odds, spread, injuries, trends for NFL Week 5

A full betting preview for NFL Week 65action between the Kansas City Chiefs and Minnesota Vikings.
Oct 1, 2023; Charlotte, North Carolina, USA; Minnesota Vikings linebacker D.J. Wonnum (98)
Oct 1, 2023; Charlotte, North Carolina, USA; Minnesota Vikings linebacker D.J. Wonnum (98) / Bob Donnan-USA TODAY Sports
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The Minnesota Vikings finally got their first win of the season in Week 4, but now have to host the defending Super Bowl champions in Week 5.

Don't fear, Vikings fans, I have faith in them making this game close and maybe even pull off the upset.

I'll break down why I think that later in this article, but if you want my best bets for the entire Week 5 slate, check out this week's edition of the "Road to 272 Bets."

Also, if you want to get in on the action this week, I'd recommend doing so PointsBet. For a limited time, new users will get up to $1,000 in second chance bets! Just click the link below to take advantage of this fantastic offer.

Chiefs vs. Vikings odds, spread, and total for NFL Week 5

Chiefs vs. Vikings betting trends

  • Chiefs are 4-2 ATS in their last six games
  • Chiefs are 11-1 straight up in their last 12 games
  • Chiefs are 8-1 ATS in their last nine games vs. NFC opponents
  • Vikings are 2-7-1 ATS in their last 10 games
  • The OVER is 8-4 in the Vikings' last 12 games
  • Vikings are 0-5 ATS in their last five home games

Chiefs vs. Vikings injury reports

Kansas City Chiefs injury report

  • Cole Christiansen - LB - Questionable
  • Nick Bolton - LB - Questionable
  • Jaylen Watson - CB - Questionable

Minnesota Vikings injury report

  • Garrett Bradbury - C - Questionable
  • Lewis Cline - S - Questionable
  • Jaren Hall - QB - Questionable

Chiefs vs. Vikings how to watch

  • Date: Sunday, Oct. 8
  • Game Time: 4:25pm EST
  • Venue: U.S. Bank Stadium
  • How to Watch (TV): CBS
  • Kansas City Chiefs Record: 3-1
  • Minnesota Vikings Record: 1-3

Chiefs vs. Vikings key players to watch

Kansas City Chiefs

Rashee Rice: The Chiefs aren't going to be able to just rely on Travis Kelce for the rest of the season, so one of their wideouts has to step up to the plate. The most likely option to do exactly that is Rashee Rice, who has the second most targets and receptions on the team. If Kansas City wants to keep up with the Minnesota offense, Rice is going to play a big role in that.

Minnesota Vikings

Alexander Mattison: A big key that any team that wants to beat the Chiefs must use is a strong running game. The more you run the ball and control the clock, the less time Patrick Mahomes will be on the field. That's why Alexander Mattison is going to play a big role this week. He's averaging 4.5 yards per carry through the first four weeks, after finally having a breakout game against the Panthers last week.

Chiefs vs. Vikings prediction and pick

Despite sitting with a 1-3 record, the Vikings have been playing some solid football so far this season. Heading into this game, the Vikings rank fifth in the NFL in Net Yards per Play. Only the Dolphins, 49ers, Ravens, and Lions rank higher in that stat.

That's right, they actually outrank the Chiefs in Net Yards per Play, who come in right behind them at sixth at +1.0.

I have some concerns about the Chiefs offense. Yes, they scored 41 points against the Bears, but they lost to the Lions and barely escaped with wins against the Jaguars and Jets.

I'm not bold enough to take the Vikings to win this game outright, but I do think it's possible. Instead, I'm going to back them to cover the spread as home underdogs.


Odds refresh periodically and are subject to change.

You can check out all of Iain's bets here!