Saints vs. Vikings prediction, odds, spread, injuries, trends for NFL Week 10

A full betting preview for the Minnesota Vikings' Week 10 matchup against the New Orleans Saints.
Nov 5, 2023; Atlanta, Georgia, USA; Minnesota Vikings running back Alexander Mattison (2)
Nov 5, 2023; Atlanta, Georgia, USA; Minnesota Vikings running back Alexander Mattison (2) / Dale Zanine-USA TODAY Sports

The Minnesota Vikings will put their four-game win streak on the line when they return home to play the New Orleans Saints on Sunday afternoon. The Vikings had one of the more improbable wins this season as they defeated the Falcons 31-28 last week, thanks to Josh Dobbs, who had to play for an injured Jaren Hall despite not having many practice reps.

As for the Saints, they are finally in first place in the NFC South after defeating the Bears 31-24 at the Caesars Superdome last Sunday. 

Can Derek Carr lead New Orleans to their third straight win? Or will Dobbs keep the Vikings’ season and playoff hopes afloat? Below, we’ll break down this Week 10 matchup and give our prediction using odds from DraftKings. 

If you are going to bet on this game, make sure to do it with our partner DraftKings! If you sign up below you will get $200 in bonus bets instantly on your first bet of $5 AND a no sweat single game parlay every day this football season! All you have to do is opt in below!

Saints vs. Vikings Odds, Spread and Total

Saints vs. Vikings Betting Trends

  • Saints are 2-6-1 ATS this season
  • The UNDER is 9-1 in New Orleans’ last 10 road games
  • Vikings are 1-3 ATS at home this season
  • Minnesota is 5-1 in its past six games

Saints vs. Vikings Injury Reports

Saints Injury Report

  • Isaiah Foskey - DE - Questionable
  • Kendre Miller - RB - Questionable
  • Ty Summers - LB - Questionable

Vikings Injury Report

  • Nick Mullens - QB - IR
  • Brian Asamoah II - LB - Questionable
  • Christian Darrisaw - OT - Questionable
  • Dean Lowry - DE - Questionable
  • Jalen Nailor - WR - Questionable

Saints vs. Vikings How to Watch

  • Date: Sunday, Nov. 12
  • Game Time: 1 p.m. EST
  • Venue: U.S. Bank Stadium
  • How to Watch (TV): FOX
  • Saints Record: 5-4
  • Vikings Record: 5-4

Saints vs. Vikings Key Players to Watch

New Orleans Saints

Chris Olave: The second-year wide receiver has established himself as the Saints’ No. 1 wide receiver despite Michael Thomas being on the roster. Olave scored his first touchdown since Week 5 in last week’s seven-point win over the Bears. The former Ohio State receiver also had six receptions (eight targets) for 46 yards. The Vikings’ defense has some playmakers in the secondary, but Olave will still see a healthy target share on Sunday.

Minnesota Vikings

Alexander Mattison: With Cam Akers out for the rest of the season, the Vikings need Mattison to be productive on the ground. The 25-year-old running back hasn’t lived up to the preseason expectations, but he still has 434 rushing yards. Mattison has yet to score a rushing touchdown this season. But he scored a receiving TD in last week’s win against the Falcons. Minnesota hopes the 5-foot-11 running back can have a breakout performance against the Saints’ defense, which is allowing 112.3 rushing yards per game this season (17th in the NFL).

Saints vs. Vikings Prediction and Pick

The Vikings have played good complimentary football lately, which has led to them winning four straight games.

Minnesota’s defense has been excellent, allowing 17 points per game over their last four games. They’ve also recorded nine takeaways over that span.

Therefore, if Dobbs can manage the game and put the offense in good situations, I trust the Vikings’ defense to do their job.

As for the Saints, their defense played well in last week’s win against the Bears, forcing five turnovers. However, New Orleans has still allowed 20-plus points in three consecutive games.

Dobbs can put a couple of scoring drives together with the weapons at WR and TE. With the spread hanging around 2.5 for Sunday’s contest, I’ll take the Vikings and the points.

Game odds refresh periodically and are subject to change